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R&D Progress

2015-03-08

Age-associated changes of cerebrospinal fluid amyloid-β and tau in cynomolgus monkeys

Jan. 31, 2014-Scientists of Wincon and University of Kentucky published their collaborative study titled Age-associated changes of cerebral fluid amyloid-β and tau in cynomolgus monkeys in Neurobiology of Aging Abstract Nonhuman primates (NHPs) are useful for the study of age-associated changes in the brain as a model that is biologically closely related to humans. For example, with age, all NHPs analyzed to date, develop β-amyloid (Aβ) plaques as seen in humans. Nevertheless, it is still unclear if NHPs have human-like age-associated changes in Aβ and tau protein in cerebrospinal fluid. The present study was an attempt to specifically address these…

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